Scientists, incurable disease, amyotrophic lateral nerve cells Skleroz'un (ALS), according to the article published in the journal buldu.Nature reason, caught the disease died within three years, nearly half of all species, the brain or spinal cord causing proteins can not be repaired.
Scientists at Northwestern University in Chicago, headed by Siddique Teepu 25 years working on the investigation by ALS, protein does not operate as a result of the repair process in patients with severely damaged nerve cells was determined.
Their discovery, the development of treatments for ALS, a completely new area to reveal that Siddique, proteins regulate the process of repair or improve said drugs could be developed.
Scientists, a protein also cause inoperative to the process of repair proteins that under normal circumstances, Ubiquilin2 protein, motor nerve cells and nerve cells are damaged or defective proteins neokorteksteki said left disabled. Scientists, however, does not work in ALS patients Ubiquilin2 protein, unlike with the damaged proteins accumulate in the nerve cells and cause their death is reported.
In patients with ALS in the family more than one gene mutation was found also Ubiquilin2. Severe muscle paralysis seen in ALS patients. The disease progresses, swallowing, talking or even breathing difficult. A type of the disease, causing dementia and the patient forgets to speak, unable to even the simplest tasks. Only 10 percent of cases, genetic. The disease mainly occurs suddenly.
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